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Product introduction
Oglemilast (GRC 3886) 是一种具有口服活性磷酸二酯酶 4 (PDE4) 抑制剂,对 PDE4D3 的 IC50 为 0.5 nM。Oglemilast 在体外和体内抑制肺细胞浸润,包括嗜酸性粒细胞增多和嗜中性粒细胞减少。Oglemilast 具有应用于炎症性气道疾病的潜力。 Oglemilast (GRC 3886) is a potent and orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 0.5 nM for PDE4D3. Oglemilast inhibits pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast has the potential for inflammatory airway diseases.
Chinese name
Oglemilast,抑制剂, 磷酸二酯酶 4 抑制剂
English name
Oglemilast
Chinese alias
-
English alias
BCP21392 | UNII-67GXQ6WCC6 | NCGC00379066-01 | GRC3886 | GRC-3886 | 4-difluoromethoxy-8-methanesulfonylamino-dibenzofuran-1-carboxylic acid (3,5-dichloro-pyridin-4-yl)-amide | N-(3,5-Dichloropyridin-4(1H)-ylidene)-4-(difluoromethoxy)-8-[(methanesulfonyl)a
CAS number
778576-62-8
molecular formula
C20H13Cl2F2N3O5S
molecular weight
516.30 g/mol
Exact mass
≥98%
PSA
119.000 Ų
Logp
4.6
Technical Documents
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Research chemical 95% 5mg

Research chemical 95% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S86487-5mg
Product model:5mg
level: 95% 5mg
Lead Time:30days
sold 169 Items
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