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Product introduction
SB203580 HCl是p38-MAPKs特异性抑制剂,其IC50值为0.6 μM。 SB203580是p38-MAPKα和p38-MAPKβ的抑制剂。在新生肌细胞中,SB203580阻止p38-MAPK激活MAPKAPK2,其IC50值为70 nM。在KB细胞中,SB203580还通过IL-1、渗透压力或亚砷酸盐显著抑制MAPKAPK2活化。在KB细胞中,SB203580也抑制IL-1、化学物质或渗透压力诱导的HSP27磷酸化,其IC50值
Chinese name
SB 203580盐酸盐
English name
SB 203580 hydrochloride
Chinese alias
4-[4-(4-氟苯基)-2-[4-(甲基亚磺酰基)苯基]-1H-咪唑-5-基]吡啶盐酸盐
English alias
4-[4-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridinehydrochloride | SB 203580 | p38 MAP Kinase Inhibitor XVI, Hydrochloride | 4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine hydrochloride
CAS number
869185-85-3
molecular formula
C21H16FN3OS.HCl
molecular weight
413.9 g/mol
Exact mass
-
PSA
77.900 Ų
Logp
-
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Research chemical ≥98% 100mg

Research chemical ≥98% 100mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S86909-100mg
Product model:100mg
level: ≥98% 100mg
Lead Time:30days
sold 413 Items
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