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Product introduction
SY-5609 (CDK7-IN-3) 是一种高选择性,非共价的 CDK7 抑制剂,KD 为 0.065 nM。SY-5609 对 CDK2 (Ki=2600 nM),CDK9 (Ki=960 nM),CDK12 (Ki=870 nM) 具有较弱的抑制作用。SY-5609 诱导肿瘤细胞凋亡并具有抗肿瘤活性。 SY-5609 (CDK7-IN-3) is a highly selective, noncovalent CDK7 inhibitor with a KD of 0.065 nM. SY-5609 shows poor inhibition on CDK2 (Ki=2600 nM), CDK9 (Ki=960 nM), CDK12 (Ki=870 nM). SY-5609 induces apoptosis in tumor cells and has antitumor activity.
Chinese name
SY-5609, 细胞周期蛋白依赖性激酶 12 抑制剂
English name
SY-5609
Chinese alias
-
English alias
CDK7-IN-3 | BDBM50583929 | 1H-Indole-6-carbonitrile, 7-(dimethylphosphinyl)-3-(2-(((3S)-6,6-dimethyl-3-piperidinyl)amino)-5-(trifluoromethyl)-4-pyrimidinyl)- | JDJOUBVVSQDIRC-AWEZNQCLSA-N | EN300-37407429 | 1H-Indole-6-carbonitrile, 7-(dimethylphosphinyl)
CAS number
2417302-07-7
molecular formula
C23H26F3N6OP
molecular weight
490.46 g/mol
Exact mass
-
PSA
106.000 Ų
Logp
2.700
Technical Documents
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Research chemical CAS 2417302-07-7 5mg

Research chemical CAS 2417302-07-7 5mg, complete specifications, for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S976235-5mg
Product model:5mg
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Lead Time:30days
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