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Product introduction
AL 8697 是一种特异性的,具有活性的 p38α MAPK 抑制剂,IC50 为 6 nM。与 p38β (IC50=82 nM) 相比,AL 8697 对 p38α 的抑制作用强 14 倍,对 p38α 的选择性比其他 91 种激酶高 300 倍。具有抗炎活性。 Product description AL 8697 is a specific and active p38α MAPK inhibitor with an IC50 of 6 nM. AL 8697 displays 14-fold greater inhibition of p38α compared to p38β (IC50=82 nM), and 300-fold selectivity for p38α over a panel of 91 kinases. Anti-inflammatory activity.
Chinese name
AL 8697,p38α抑制剂
English name
AL 8697
Chinese alias
N-环丙基-3-[3-(1,1-二甲基乙基)-6,8-二氟-1,2,4-三唑[4,3-a]吡啶-7-基] -5-氟-4-甲基苯甲酰胺
English alias
N-Cyclopropyl-3-[3-(1,1-dimethylethyl)-6,8-difluoro-1,2,4-triazolo[4,3-a]pyridin-7-yl]-5-fluoro-4-methylbenzamide | 3-(3-(tert-butyl)-6,8-difluoro-[1,2,4]triazolo[4,3-a]pyridin-7-yl)-N-cyclopropyl-5-fluoro-4-methylbenzamide
CAS number
1057394-06-5
molecular formula
C21H21F3N4O
molecular weight
402.41 g/mol
Exact mass
≥98%(HPLC)
PSA
59.300 Ų
Logp
5
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MedMol AL 8697 98% 5mg

MedMol AL 8697 98% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T26481-5mg
Product model:5mg
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Lead Time:30days
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