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Product introduction

AG879是酪氨酸激酶的抑制剂，能够抑制TrKA的磷酸化，但不能抑制TrKB 和TrKC，也是高选择性的ErbB2激酶抑制剂。A protein tyrosine kinase inhibitor with potent effects on TrkA TyrphostinAG879 is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation, but not TrKB and TrKC.[1] also a ErbB2 kinase inhibitor, has at least 500-fold higher selectivity to ErbB2 (IC50 = 1 μmol/L) than EGFR (IC50 >500 μmol/L). A protein tyrosine kinase inhibitor with potent effects on TrkA

Specs ⸢ View details ⸥

Chinese name

Tyrphostin AG 879 酪氨酸激酶的抑制剂

English name

Tyrphostin AG 879

Chinese alias

English alias

CAS number

148741-30-4

molecular formula

C18H24N2OS

molecular weight

316.46 g/mol

Exact mass

PSA

102.000 Å²

Logp

4.700

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Consultation

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