- Treatment： 如发生过量，应采取基本措施确保气道通畅，并监测心血管和呼吸系统。通常，停用替扎尼定并给予适当治疗后，症状会在一到三天内缓解。由于作用机制相似，替扎尼定过量的症状和管理与可乐定过量后的症状和管理相似。(L1712)
- exposure pathway： 口服
- Harmful effect： * 用于BRAF突变阳性恶性肿瘤的维莫非尼是CYP1A2抑制剂，可增加替扎尼定的血浆浓度，导致潜在毒性。
- Toxicity summary： 替扎尼定通过在α2-肾上腺素受体位点发挥激动剂作用，增加运动神经元的前突触抑制，从而减少痉挛。
- Regulatory information： REACH注册物质：状态：活跃 更新：22-01-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/21940
- Health Effects： 可能引起潜在危险的皮疹，可能发展为史蒂文斯-约翰逊综合征，这是一种极其罕见但可能致命的皮肤疾病。
- Hepatotoxicity： 可能性评分：C(可能是临床上明显的肝损伤的罕见原因)。
- Hazard categories and classifications： 代表物2 (66.7%)
- Carcinogen Classification： 对人类无致癌性迹象（未被IARC列出）。
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： ◉ 对哺乳和母乳的影响
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Research chemical 96%; 100mg
Research chemical 96%; 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 96%; 100mg.
