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Product introduction

Eg5抑制剂V，trans-24是可透过细胞的HR22C16衍生物，对有丝分裂驱动蛋白Eg5-ATPase活性具有增强的效价（对于trans-24和HR22C16，IC | 50 | = 0.65 vs. 4.3 µM），几乎没有或没有针对其他9种驱动蛋白的活性。显示可诱导HeLa细胞（20 µM）的单星形表型。 Eg5 Inhibitor V, trans-24 is a cell-permeable HR22C16 derivative that exhibits much enhanced potency against mitotic kinesin Eg5-ATPase activity (IC|50|= 0.65 vs. 4.3 μM for trans-24 and HR22C16, respectively) and little or no activity against 9 other kinesins. Shown to induce monoastral phenotype in HeLa cells (20 μM).

Specs ⸢ View details ⸥

Chinese name

Eg5抑制剂V，trans-24

English name

Eg5 Inhibitor V, trans-24

Chinese alias

English alias

(10R,15S)-13-benzyl-10-(3-hydroxyphenyl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione | (5R,11AS)-2-benzyl-5-(3-hydroxyphenyl)-5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione | AKOS040733

CAS number

869304-55-2

molecular formula

C26H21N3O3

molecular weight

423.5 g/mol

Exact mass

≥98%

PSA

76.600 Å²

Logp

3.900

Technical Documents

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Trans-24 ≥98% 1mg

Name: Trans-24 ≥98% 1mg
Brand: 源叶
SKU: T60833-1mg

Yuanye Trans-24 ≥98% 1mg, CAS 869304-55-2, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T60833-1mg

Product model：1mg

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Lead Time：30days

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Trans-24 ≥98% 1mg

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