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Product introduction

Taraxerone is isolated from Sedum sarmentosum . Taraxerone enhances effects on alcohol dehydrogenase ( ADH ) and acetaldehyde dehydrogenase ( ALDH ) activities with EC 50 values of 512.42 and 500.16 μM, respectively In Vivo Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure . Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:EC50: 512.42 μM (ADH),500.16 μM (ALDH)

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Chinese name

Taraxerone

English name

Taraxerone

Chinese alias

蒲公英酮

English alias

3(2H)-PICENONE, 1,4,4A,5,6,6A,8,8A,9,10,11,12,12A,12B,13,14,14A,14B-OCTADECAHYDRO-4,4,6A,8A,11,11,12B,14B-OCTAMETHYL-, (4AR-(4Aalpha,6Abeta,8Abeta,12Abeta,12Balpha,14Aalpha,14Bbeta))- | MS-27476 | D-Friedoolean-14-en-3-one | 4,4,6a,8a,11,11,12b,14b-Octame

CAS number

514-07-8

molecular formula

C30H48O

molecular weight

424.70 g/mol

Exact mass

≥98%

PSA

17.100 Å²

Logp

9.000

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