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Product introduction

TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC 50 value of 7 nM for human TLR9 . TLR9-IN-1 can be used for researching diseases associated with undesirable immune response In Vitro TLR9-IN-1 (compound no.29) (0-10 μM; 24 h) exhibits moderately inhibitory activity against IL-1b with an IC 50 of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L, RNA oligonucleotide). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:human TLR9 7 nM (IC 50 )

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Chinese name

TLR9-IN-1

English name

TLR9-IN-1

Chinese alias

English alias

CAS number

2226366-86-3

molecular formula

C23H31N7O

molecular weight

421.54 g/mol

Exact mass

≥99%

PSA

Logp

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