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Product introduction

Tafamidis meglumine (Fx-1006A) 是一种有效、选择性的 transthyretin (TTR) 稳定剂，对野生型 WT-TTR 和突变型同源四聚体 V30M-TTR，V122I-TTR 的活性相当，EC50 值为 2.7-3.2 μM。Tafamidis meglumine 抑制淀粉样蛋白的生成。 Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis

Specs ⸢ View details ⸥

Chinese name

Tafamidis meglumine, 转甲状腺素稳定剂

English name

Tafamidis meglumine

Chinese alias

他发米帝司甲葡胺 | 氯苯唑酸甲葡胺盐 | 氯苯那敏葡甲胺

English alias

CAS number

951395-08-7

molecular formula

C21H24Cl2N2O8

molecular weight

503.33 g/mol

Exact mass

≥99%

PSA

177.000 Å²

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