4-甲基伞形酮钠盐是透明质酸（HA）合成的选择性抑制剂。HA是恶性肿瘤转移中的主要成分。研究表明，在4-甲基伞形酮钠盐存在下，细胞的增殖，迁移和生长受到抑制，而细胞凋亡被诱导。另外，成纤维细胞细胞系NIH / 3T3的运动性和细胞生长受到抑制。人们认为4-甲基伞形酮钠盐可通过消耗HA合成的常用底物UDP-葡萄糖醛酸来起抑制剂的作用。还认为4-甲基伞形酮钠盐可以抑制HA合酶的表达。 4-Methylumbelliferone sodium salt is a selective inhibitor of Hyaluronan (HA) synthesis. HA is a major component in the metastasis of malignant tumors. Studies indicate that in the presence of 4-Methylumbelliferone sodium salt cell proliferation, migration, and growth are inhibited, while apoptosis is induced. In addition, the motility and cell growth was inhibited in fibroblast cell line NIH/3T3 . 4-Methylumbelliferone sodium salt is thought to function as an inhibitor via the depletion of UDP-glucuronic acid, the common substrate for HA synthesis. It is also believed that 4-Methylumbelliferone sodium salt can suppress the expression of HA-synthase.