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Product introduction
TC ASK 10 (Compound 10) 是一种有效的,选择性的,口服活性的细胞凋亡信号调节激酶 1 (ASK1) 抑制剂,IC50 为 14 nM。TC ASK 10 对其他代表性激酶的抑制活性低于 50%,ASK2 除外 (IC50 为 0.51 μM)。 TC ASK 10 is a potent ASK1 inhibitor. It displays selectivity for ASK1 over other kinases including ASK2, MEKK1, TAK1, IKKb, ERK1, JNK1, p38a, GSK-3b, PKC╬╕ and B-raf. It blocks downstream JNK1/p38 phosphorylation in cells.
Chinese name
TC ASK 10,ASK1抑制剂
English name
TC ASK 10
Chinese alias
4-(1,1-二甲基乙基)-N-[6-(1H-咪唑-1-基)咪唑并[1,2-a]吡啶-2-基]苯甲酰胺二盐酸盐
English alias
4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide dihydrochloride | N-(6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl)-4-(tert-butyl)benzamide dihydrochloride
CAS number
1005775-56-3
molecular formula
C21H21N5O.2HCl
molecular weight
432.35 g/mol
Exact mass
≥98%
PSA
64.200 Ų
Logp
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MedMol TC ASK 10 98% 10mg

MedMol TC ASK 10 98% 10mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T84452-10mg
Product model:10mg
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Lead Time:30days
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