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Product introduction
Gilteritinib 是小分子FLT3/AXL抑制剂,对FLT3和AXL的IC50值为0.29 nM和0.73 nM。其抑制c-KIT的IC50值约为抑制FLT3的800倍。 product description: Gilteritinib (ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM).
Chinese name
吉特替尼, 酪氨酸蛋白激酶受体 UFO 抑制剂
English name
Gilteritinib
Chinese alias
-
English alias
GILTERITINIB [WHO-DD] | Gilteritinib HCl | NCGC00481652-01 | AS-35199 | GILTERITINIB [MI] | 1,4-Oxadiazole, 2-(o-hydroxyphenyl)- | 2-Pyrazinecarboxamide, 6-ethyl-3-((3-methoxy-4-(4-(4-methyl-1-piperazinyl)-1-piperidinyl)phenyl)amino)-5-((tetrahydro-2H-pyr
CAS number
1254053-43-4
molecular formula
C29H44N8O3
molecular weight
552.7115 g/mol
Exact mass
-
PSA
121.000 Ų
Logp
3.5
Technical Documents
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Research chemical CAS 1254053-43-4 1ml

Yuanye Research chemical CAS 1254053-43-4 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T92543-1ml
Product model:1ml
level: 1ml
Lead Time:30days
sold 127 Items
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