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Product introduction
Ticlopidine是噻吩并吡啶类化合物,是4,5,6,7-四氢噻吩[3,2-c]吡啶,其中氮上连接的氢被邻氯苄基取代。它具有纤维蛋白调节药物、血液学药物、抗凝剂、血小板聚集抑制剂和P2Y12受体拮抗剂的作用。它是噻吩并吡啶类化合物和单氯苯类化合物。
Chinese name
噻氯匹啶, CYP2B6 抑制剂
English name
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
Chinese alias
-
English alias
BRN 1216802 | NCGC00016872-10 | PCR 5332; Ticlid; Ticlop;Tiklyd | BSPBio_000173 | Q420571 | Ticlopidin-Puren | 5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine # | BPBio1_000191 | DB00208 | EINECS 259-498-5 | MLS006011439 | STK589340 | 5-(2-chlo
CAS number
55142-85-3
molecular formula
C14H14ClNS
molecular weight
263.8
Exact mass
-
PSA
31.5
Logp
3.6
Safety
  • Hepatotoxicity: Ticlopidine在治疗期间约有4%的患者出现血清酶升高。这些升高通常是轻微的、无症状的,很少需要调整剂量或停药。Ticlopidine也与明显的急性肝损伤有关。虽然这些反应罕见,但文献中已报道超过50例,其中一些病例严重。症状发作通常在6周内(范围1至24周),表现为疲劳、黄疸和瘙痒。肝酶升高的通常模式是胆汁淤积型(~75%),但也有描述混合型或肝细胞酶升高的病例。免疫过敏特征如发热、皮疹和嗜酸性粒细胞增多可能发生但不常见,如果存在,则...
  • Other safety information: 化学品评估:IMAP评估 - 噻吩并[3,2-c]吡啶,5-[(2-氯苯基)甲基]-4,5,6,7-四氢-: 人类健康I级评估
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
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Research chemical CAS 55142-85-3 1ml

Research chemical CAS 55142-85-3 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T94117-1ml
Product model:1ml
level: 1ml
Lead Time:30days
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