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Product introduction

Quizartinib (AC220)是一种二代FLT3抑制剂，作用于Flt3(ITD/WT)，IC50为1.1 nM/4.2 nM，作用于Flt3比作用于KIT， PDGFRA， PDGFRB， RET，和CSF-1R选择性高10倍。Phase 3。An Flt-3/Flk-2 inhibitor. Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Phase 3. An Flt-3/Flk-2 inhibitor.

Specs ⸢ View details ⸥

Chinese name

奎扎替尼 (AC220), 集落刺激因子 1 受体抑制剂

English name

Quizartinib (AC220)

Chinese alias

English alias

NCGC00242493-02 | N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea | NCI60_041312 | quizartinibum | AC220 | AC-220 | SMR004703000 | vanflyta | SCHEMBL72923 | CVWXJKQAOSCOAB-UHFFFAOYSA-N | Ur

CAS number

950769-58-1

molecular formula

C29H32N6O4S

molecular weight

560.68 g/mol

Exact mass

PSA

134.000 Å²

Logp

5.600

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Research chemical CAS 950769-58-1 1ml

Name: Research chemical CAS 950769-58-1 1ml
Brand: 源叶
SKU: T94643-1ml

Yuanye Research chemical CAS 950769-58-1 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T94643-1ml

Product model：1ml

level： 1ml

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