Fosifloxuridine nafalbenamide (NUC-3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. Fosifloxuridine nafalbenamide has anticancer activity. Fosifloxuridine nafalbenamide has the potential to evoke a host immune response and enhance immunoresearch. In Vitro Fosifloxuridine nafalbenamide induces the release of damage-associated molecular patterns (DAMPs), with increased expression of calreticulin (CRT) at the cell surface and concomitant loss of nuclear nuclear high mobility group box protein 1 (HMGB1). MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Fosifloxuridine nafalbenamide exhibits anti-cancer activity in HT-29 nude mouse xenograft models. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid