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Product introduction

ATI-2341 TFA是一种有效的 C-X-C 趋化因子受体 4 型 (CXCR4) 功能选择性变构激动剂，其作为偏向配体起作用，有利于 Gα1激活而不是 Gα13。ATI-2341 TFA激活抑制性异源三聚体 G 蛋白 (Gi) 以促进 cAMP 产生的抑制并诱导钙动员。ATI-2341TFA 是一种有效骨髓多形核中性粒细胞 (PMNs) 和造血干细胞和祖细胞 (HSPCs) 动员剂。 Biochemical Mechanism ATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4) that functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 does not promote β-arrestin recruitment. ATI-2341 promotes the mobilization of PMNs and HSPCs in the peripheral circulation of both mice and monkeys.

Specs ⸢ View details ⸥

Chinese name

ATI-2341 TFA

English name

ATI-2341 TFA

Chinese alias

ATI-2341 三氟乙酸

English alias

(2S,3Z,5S,6Z,8S,9Z,11S,12Z,14S)-11-(4-aminobutyl)-14-((Z)-((2S,3Z,5S,6Z,8S,9Z,11S,12Z,14S,15Z,17S,18Z,20S,21Z,23S,24Z,26S,27Z,30Z,32S,33Z)-17,20-bis(4-aminobutyl)-11-(3-guanidinopropyl)-1,4,7,10,13,16,19,22,25,28,31,34-dodecahydroxy-23-(3-hydroxy-3-iminop

CAS number

1337878-62-2

molecular formula

C104H178N26O25S2

molecular weight

2256.82 g/mol

Exact mass

10mM in DMSO

PSA

917.000 Å²

Logp

-1.600

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Research chemical CAS 1337878-62-2 1ml

Name: Research chemical CAS 1337878-62-2 1ml
Brand: 源叶
SKU: T95647-1ml

Yuanye Research chemical CAS 1337878-62-2 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T95647-1ml

Product model：1ml

level： 1ml

Lead Time：30days

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Research chemical CAS 1337878-62-2 1ml

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