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RITA (NSC 652287)诱导DNA-蛋白质和DNA-DNA交联,检测不到DNA单链断裂,通过靶向作用于p53,也抑制MDM2-p53相互作用。A trycyclic thiophene derivative that binds MDM2, activates p53 and induces apoptosis. RITA (NSC 652287) induces both DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks, and also inhibits MDM2-p53 interaction by targeting p53. A trycyclic thiophene derivative that binds MDM2, activates p53 and induces apoptosis.
Chinese name
RITA (NSC 652287),p53激活剂
English name
RITA (NSC 652287)
Chinese alias
5,5'-(2,5-呋喃二基)二-2-噻吩甲醇
English alias
BCP06744 | J-504944 | FT-0703160 | HMS3269E07 | [5-[5-[5-(hydroxymethyl)-2-thiophenyl]-2-furanyl]-2-thiophenyl]methanol | AKOS024457101 | EX-A138 | Thiophene-2-methanol,5'-(2,5-furandiyl)bis- | NCIChal_000017 | BRD-K00317371-001-01-2 | NCI60_018346 | HMS3
CAS number
213261-59-7
molecular formula
C14H12O3S2
molecular weight
292.37 g/mol
Exact mass
≥98%
PSA
110.000 Ų
Logp
2.000
Technical Documents
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Research chemical CAS 213261-59-7 1ml

Yuanye Research chemical CAS 213261-59-7 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T97004-1ml
Product model:1ml
level: 1ml
Lead Time:30days
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