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Product introduction

Vodobatinib (K0706) 是一种有效的第三代，且具有口服活性的 Bcr-Abl1 酪氨酸激酶抑制剂，IC50 为 7 nM。Vodobatinib 对大多数 BCR-ABL1 点突变体具有活性，对 BCR-ABL1T315I 无活性。 Vodobatinib 可用于慢性粒细胞白血病 (CML) 研究。 Product description： Vodobatinib (K0706) is a potent, third generation and orally active Bcr-Abl1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants, and has no activity against BCR-ABL1T315I. Vodobatinib can be used for chronic myeloid leukemia (CML) research

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Chinese name

Vodobatinib (K0706), ABL 原癌基因 1 抑制剂

English name

Vodobatinib (K0706)

Chinese alias

English alias

CAS number

1388803-90-4

molecular formula

C27H20ClN3O2

molecular weight

453.9 g/mol

Exact mass

PSA

71.100 Å²

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