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Product introduction

WP1066是一种新型JAK2和STAT3抑制剂，在HEL细胞中IC50分别为2.30 μM和2.43 μM；对JAK2，STAT3，STAT5和ERK1/2具有抑制活性，而对JAK1和JAK3没有作A cell permeable inhibitor of Stat3 and JAK2 protein tyrosine kinase. WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. A cell permeable inhibitor of Stat3 and JAK2 protein tyrosine kinase.

Specs ⸢ View details ⸥

Chinese name

WP1066,JAK / STAT3抑制剂, K v1.3通道阻断剂

English name

WP1066

Chinese alias

English alias

CAS number

857064-38-1

molecular formula

C17H14BrN3O

molecular weight

356.22 g/mol

Exact mass

PSA

65.800 Å²

Logp

3.400

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