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Product introduction
WZ3146是不可逆的EGFR(L858R)和EGFR(E746_A750)突变选择型抑制剂,IC50均为2 nM,对ERBB2磷酸化(T798I)无抑制性。A mutant EGFR phosphorylation inhibitor WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I). A mutant EGFR phosphorylation inhibitor
Chinese name
WZ3146
English name
WZ3146
Chinese alias
-
English alias
A891789 | n',n'-diisopropyl-ethane-1,2-diamine | AS-55862 | N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide | STL377914 | SW219394-1 | D70853 | N-[3-({5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl
CAS number
1214265-56-1
molecular formula
C24H25ClN6O2
molecular weight
464.96 g/mol
Exact mass
≥98%
PSA
82.600 Ų
Logp
4.3
Technical Documents
「No technical documents」
Related
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WZ3146 10mM in DMSO 1ml

WZ3146 10mM in DMSO 1ml Macklin 1214265-56-1, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:W793184-1ml
Product model:1ml
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Lead Time:30days
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