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Product introduction
XL019 是一种有效的、口服活性的、选择性的 JAK2 抑制剂,对 JAK2,JAK1,JAK3 的 IC50 分别为 2.2、134.3、214.2 nM。XL019 对JAK2的选择性是 100 多种丝氨酸/苏氨酸和酪氨酸激酶(包括 JAK 家族的其他成员)的 50 倍或更高。XL019 对 JAK2 V617F 和野生型 JAK2 细胞中 STAT3 和 STAT5 磷酸化的抑制作用。
Chinese name
XL019, Janus 激酶 1 抑制剂
English name
XL019
Chinese alias
-
English alias
SCHEMBL4382715 | Lycoran-1.alpha., 3,3a-didehydro- | 4L1AM42NVA | MFCD24386874 | A859333 | SW219757-1 | 3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-(nonylphenoxy)- | GTPL7971 | OXOTHIAZOLIDINECARBOXYLIC ACID [INCI] | NCGC00381563-04 | VMB75556 | HY-137
CAS number
945755-56-6
molecular formula
C25H28N6O2
molecular weight
444.53 g/mol
Exact mass
-
PSA
91.400 Ų
Logp
2.800
Technical Documents
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Consultation

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XL019 >95% 5mg

XL019 >95% 5mg CAS 945755-56-6, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:X860865-5mg
Product model:5mg
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Lead Time:30days
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