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Product introduction

YUM70 是一种有效的 glucose-regulated protein 78 (GRP78) 抑制剂，IC50 为 1.5 μM。YUM70 在胰腺癌中诱导内质网 (endoplasmic reticulum, ER) 应激介导的细胞凋亡。 Information YUM70 is a potent inhibitor ofglucose-regulated protein 78 (GRP78)inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.

Specs ⸢ View details ⸥

Chinese name

YUM70

English name

YUM70

Chinese alias

English alias

Butanamide,N-[1,3-benzodioxol-5-yl(5-chloro-8-hydroxy-7-quinolinyl)methyl]-

CAS number

423145-35-1

molecular formula

C21H19ClN2O4

molecular weight

398.84 g/mol

Exact mass

10mM in DMSO

PSA

80.700 Å²

Logp

4.500

Technical Documents

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