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Product introduction
产品介绍: Ziritaxestat (GLPG1690)是选择性的自毒素抑制剂,IC50为131 nM,Ki值为15 nM。 Information Ziritaxestat (GLPG1690) Ziritaxestat (GLPG1690) is a selective autotaxin inhibitor with an IC50 of 131 nM and Ki of 15 nM. Targets Autotaxin 15 nM(Ki) In vivo Ziritaxestat (GLPG1690) decreases LPA levels in a sustainable manner, in mouse plasma, from a dose of 3 mg/kg onward. It demonstrates significant activity in the mouse BLM-induced fibrosis model at doses of 10 and 30 mg/kg twice a day.
Chinese name
Ziritaxestat (GLPG1690), Autotaxin 抑制剂
English name
Ziritaxestat (GLPG1690)
Chinese alias
齐利他司他 (GLPG1690)
English alias
(2-Amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetic acid # | AC-36149 | GLPG-1690(Ziritaxestat) | MFCD31544330 | Ziritaxestat [USAN] | WHO 11017 | GTPL9561 | 2-[[2-Ethyl-8-Methyl-6-[4-[2-(3-Oxidanylazetidin-1-Yl)-2-Oxidanylidene-Ethyl]piperazin-1-Yl]imidaz
CAS number
1628260-79-6
molecular formula
C30H33FN8O2S
molecular weight
588.7 g/mol
Exact mass
-
PSA
132.000 Ų
Logp
4.8
Technical Documents
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Ziritaxestat (GLPG1690), Autotaxin inhibitor 1ml

Ziritaxestat (GLPG1690), Autotaxin inhibitor 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.

item number:Z421990-1ml
Product model:1ml
level: 1ml
Lead Time:30days
sold 910 Items
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Specifications:

1ml

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